KMID : 1130320070500090901
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Korean Journal of Pediatrics 2007 Volume.50 No. 9 p.901 ~ p.904
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Clinical and Radiological Analysis of Reversible Posterior Leukoencephalopathy Syndrome in Children
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Lim Hae-Ri
Kwon Soon-Hak Seo Hye-Eun
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Abstract
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Purpose : Clinical and radiologic findings that mainly involve the white/gray matter of the parieto-occipital lobes. The purpose of this study was to determine its clinical and radiological characteristics.
Methods : A total of 15 pateints were involved in the study. Their medical records and radiological features of brain MRI were retrospectively reviewed and analyzed.
Results : Fifteen pateints were involved. (9 males and 5 females). The patients¡¯ ages ranged from 2-20 years (mean age:10 years). The brain MRI revealed fairly symmetric areas of increased T2 signal involving both white and gray matter of parieto-occipital regions. The condition seemed to be associated with cyclosporin A and steroid therapy or a variety of other conditions in which blood pressure rises acutely.
Conclusion : Reversible posterior leukoencephalopathy syndrome is a complicated neurological condition, but a better understanding of this complex syndrome may obviate unnecessary investigations and lead to prompt and appropriate management of the associated problems.
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KEYWORD
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Leukoencephalopathy, Seizure, Cyclosporin, Steroid
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